Understanding how genes are regulated during early embryo development
A novel epigenetic mechanism in early embryogenesis
This study looks at how certain genes and their changes affect the early development of embryos, helping us understand how cells become different types of tissues, which is important for healthy growth and could have implications for reproductive health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10813151 on NIH RePORTER |
What this research studies
This research investigates the role of specific genetic elements and modifications in the early stages of embryo development. It focuses on how changes in chromatin structure and DNA methylation influence the ability of cells to develop into various types of tissues. By studying these mechanisms, the research aims to uncover how certain genes are activated or silenced during embryogenesis, which is crucial for proper development. The findings could provide insights into the fundamental processes that govern early life and potential implications for reproductive health.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals interested in the genetic factors affecting embryonic development or those with a history of reproductive issues.
Not a fit: Patients with established developmental disorders unrelated to genetic mechanisms studied in this research may not benefit directly.
Why it matters
Potential benefit: If successful, this research could lead to advancements in understanding developmental disorders and improving reproductive health.
How similar studies have performed: Other research has shown promising results in understanding genetic regulation during embryogenesis, indicating that this approach has potential for significant discoveries.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Xiao, Zhuo Andrew — Yale University
- Study coordinator: Xiao, Zhuo Andrew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.