Understanding how genes are controlled inside cells
Cytoplasmic mechanisms of gene regulation: intersections and coordination
This project explores how different processes work together inside our cells to manage gene activity, which is important for understanding conditions like cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11128737 on NIH RePORTER |
What this research studies
Our cells have many ways to control which genes are active and when, like turning them on or off or adjusting how much protein they make. This project looks at how these different control systems, including how proteins are broken down, interact with each other. By studying these fundamental processes in fruit flies, we hope to uncover new insights into how gene regulation works during early development. This basic understanding can help us learn more about what goes wrong in diseases like cancer.
Who could benefit from this research
Good fit: Patients interested in the basic biological mechanisms underlying diseases like cancer, even if the immediate research involves model organisms, would find this relevant.
Not a fit: Patients seeking immediate clinical trials or direct treatment options would not find direct benefit from this foundational laboratory research.
Why it matters
Potential benefit: If successful, this work could provide a deeper understanding of fundamental cellular processes that go awry in diseases like cancer, potentially leading to new ways to think about treatments.
How similar studies have performed: This project builds upon previous discoveries from the research team, suggesting a foundation of prior successful work in this area.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Rissland, Olivia Selfridge — University of Colorado Denver
- Study coordinator: Rissland, Olivia Selfridge
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.