Understanding how genes and metabolites affect lung function in asthma over time
Omic Determinants of Longitudinal Lung Function in Asthma
This study is looking at how certain genes and substances in the body affect lung health in adults with asthma over time, hoping to find clues that can help predict when lung function might get worse, so that people with asthma can get better care and support.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11142424 on NIH RePORTER |
What this research studies
This research investigates how specific genes and metabolites influence lung function in adults with asthma over time. By analyzing genomic and metabolomic data, the study aims to identify biological markers that can predict lung function deterioration. The approach includes using electronic medical records to track lung function changes and correlate them with genetic and metabolic profiles. This could lead to better understanding and management of asthma, particularly for those at risk of severe lung issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with asthma who are experiencing changes in their lung function.
Not a fit: Patients without a diagnosis of asthma or those with stable lung function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized treatment strategies that improve lung function and reduce asthma-related complications.
How similar studies have performed: Previous research has shown promise in using genomic and metabolomic profiling to understand asthma, indicating that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Mcgeachie, Michael John — Brigham and Women's Hospital
- Study coordinator: Mcgeachie, Michael John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.