Understanding how genes and environment interact to affect health
Official title: Characterizing and modeling the genomewide molecular basis of gene-environment interactions
Funded at North Carolina State University Raleigh · NIH-11092892 · Data updated 2026-11-12
This study looks at how your genes and your environment work together to affect your health, helping us understand why people can have different health outcomes based on their unique situations.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project start | August 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $380,000 |
| NIH project number | 5R35GM151048-03 |
| Project ID | NIH-11092892 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with known genetic variations who are experiencing health issues potentially influenced by their environment.
✕Less likely to help
Patients without significant genetic variations or those living in stable environments may not benefit from this research.
What this research studies
This research investigates how genetic variations interact with environmental factors to influence individual health and well-being. By examining gene-environment interactions (GxE), the study aims to uncover the molecular mechanisms that lead to differences in health outcomes among individuals in varying environments. The approach involves analyzing genomic data and environmental influences to create predictive models that can better explain these interactions. Patients may benefit from insights into how their genetic makeup and surroundings affect their health.
Why it matters
Potential benefit: If successful, this research could lead to personalized health strategies that consider both genetic and environmental factors.
How similar studies have gone: Previous research has shown promising results in understanding gene-environment interactions, but this study aims to explore novel aspects of these complex relationships.
Where this research is happening
-
North Carolina State University Raleigh
Raleigh, United States Active
Researchers
- Principal investigator: Gage, Joseph Lee — North Carolina State University Raleigh
- Study coordinator: Gage, Joseph Lee
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.