Understanding how genes and environment affect asthma in different populations
Official title: Integrating polygenic and environmental risk factors for asthma in diverse populations
Funded at Harvard Medical School · NIH-10916180 · Data updated 2026-11-12
This study is looking at how both your genes and your surroundings can affect asthma, with the goal of finding better ways to predict and manage the condition for everyone, especially those who might be more at risk.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | April 1, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $36,856 |
| NIH project number | 5F31HL167378-02 |
| Project ID | NIH-10916180 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with a family history of asthma or those living in environments with known asthma triggers.
✕Less likely to help
Patients with asthma that is solely caused by non-genetic factors or those who do not have access to the necessary environmental data may not benefit from this research.
What this research studies
This research investigates the complex relationship between genetic and environmental factors that contribute to asthma, a common inflammatory airway disease. By analyzing data from diverse populations, the study aims to create more accurate models for predicting asthma risk based on both genetic predispositions and environmental exposures. The researchers will utilize advanced statistical methods to develop polygenic risk scores and assess how these scores can improve asthma management and prevention strategies. This approach seeks to address health disparities in asthma prevalence and outcomes across different demographic groups.
Why it matters
Potential benefit: If successful, this research could lead to improved asthma risk prediction and more personalized treatment strategies for patients.
How similar studies have gone: Previous research has shown promise in using genetic and environmental factors to predict asthma risk, indicating that this approach has potential for success.
Where this research is happening
-
Harvard Medical School
Boston, United States Active
Researchers
- Principal investigator: Tsuo, Kristin May — Harvard Medical School
- Study coordinator: Tsuo, Kristin May
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.