Understanding how genes and chromatin work together in cells
Single-cell analysis and synthetic control of mammalian chromatin dynamics and gene regulation
This study is looking at how our genes and the way they are packaged in our cells work together, especially as we age or when diseases like cancer develop, to help find new ways to treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11001522 on NIH RePORTER |
What this research studies
This research investigates the complex interactions between genes and chromatin, which are crucial for various biological processes such as aging and disease progression, including cancer. By utilizing advanced techniques in synthetic biology and single-cell analysis, the study aims to uncover how these interactions change over time and differ between individual cells. This approach allows for a more detailed understanding of gene regulation and the factors influencing cell behavior, which could lead to new therapeutic strategies. Patients may benefit from insights gained about how gene regulation affects their specific conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions related to gene regulation, such as cancer or age-related diseases.
Not a fit: Patients with conditions unrelated to gene regulation or chromatin dynamics may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that target gene regulation to improve health outcomes in diseases like cancer.
How similar studies have performed: Other research has shown promising results in understanding gene regulation through similar high-throughput and single-cell approaches, indicating potential for success in this area.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Bintu, Lacramioara — Stanford University
- Study coordinator: Bintu, Lacramioara
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.