Understanding how genes and brain connections influence nicotine addiction
A Multivariate Mediation and Deep Learning Framework for Genome-Connectome -Substance Use Research
This study is looking at how your genes and brain connections work together to influence nicotine addiction, with the hope of finding better, personalized treatments that could also help with other substance use issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10684291 on NIH RePORTER |
What this research studies
This research investigates the complex relationship between genetic factors and brain circuitry in the context of nicotine addiction. By utilizing advanced statistical methods and deep learning algorithms, the study aims to identify how various genetic variants interact to affect brain function and structure, ultimately influencing addiction traits. Patients may benefit from insights gained about the biological underpinnings of their addiction, which could lead to more personalized treatment approaches. The research will also explore the applicability of its findings to other substance use disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with nicotine dependence or addiction.
Not a fit: Patients who do not have a history of substance use or those not affected by nicotine addiction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatments for nicotine addiction and potentially other substance use disorders.
How similar studies have performed: Previous research has shown promise in using genetic and neuroimaging data to understand addiction, suggesting that this approach could yield valuable insights.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Chen, Shuo — University of Maryland Baltimore
- Study coordinator: Chen, Shuo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.