Understanding how genes affect nutrition and immunity in newborns
Investigating the role of gene regulatory networks in neonatal nutrition and immunity
This study is looking at how newborns' intestines learn to absorb nutrients and build their immune systems, which could help improve their health, and it's for anyone interested in understanding how babies grow and stay healthy.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11069318 on NIH RePORTER |
What this research studies
This research investigates the critical period of neonatal development, focusing on how the intestine absorbs nutrients and establishes immune defenses against pathogens. The study examines the role of specific transcription factors that are essential for nutrient uptake and immune function in newborns. By exploring the connections between nutrition and immune development, the research aims to uncover mechanisms that could lead to better health outcomes for infants. The approach includes genetic analysis and bioinformatics to understand how these factors influence growth and immune responses.
Who could benefit from this research
Good fit: Ideal candidates for this research include newborns and infants who may be at risk for nutritional deficiencies or immune system challenges.
Not a fit: Patients who are older than infancy or those with established immune disorders unrelated to nutritional factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved nutritional strategies and interventions that enhance immune function in newborns, potentially reducing the risk of malnutrition and related health issues.
How similar studies have performed: Previous research has shown promising results in understanding the role of nutrition in immune development, but this specific approach focusing on gene regulatory networks in neonates is relatively novel.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Scales, Michael Kemper — Duke University
- Study coordinator: Scales, Michael Kemper
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.