Understanding how genes affect human diseases using model organisms
Bioinformatics Section
This study is looking at how certain genetic changes can affect diseases by using specially modified animals, and the goal is to help patients by finding better ways to target these genetic issues in treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10898623 on NIH RePORTER |
What this research studies
This research focuses on using model organisms to explore the impact of specific genetic variants on human diseases. By engineering these organisms with targeted genetic changes, researchers aim to accurately annotate genetic variants and assess their effects on various phenotypes. Advanced bioinformatics tools will be developed to integrate and analyze data from these models, facilitating a better understanding of the molecular mechanisms behind diseases. Patients may benefit from insights gained through this research, which could lead to improved genetic targeting strategies in clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with genetic conditions that could be modeled using animal models.
Not a fit: Patients with conditions that do not have a genetic basis or cannot be modeled in animals may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic contributions to diseases, potentially leading to more effective treatments.
How similar studies have performed: Previous research has shown success in using model organisms to study genetic variants, indicating that this approach is both established and promising.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Milosavljevic, Aleksandar — Baylor College of Medicine
- Study coordinator: Milosavljevic, Aleksandar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.