Understanding how genes affect diabetes through advanced data analysis

GeneSight: Advancing Insights into Complex Genetic Traits through CFDE-Enhanced Knowledge Graphs

['FUNDING_R03'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-10990226

This study is working on a smart tool that uses computer technology to help us understand the genetic reasons behind adult-onset diabetes, so that patients can get better treatment options based on this information.

Quick facts

Phase['FUNDING_R03']
Study typeNih_funding
SexAll
SponsorUNIV OF NORTH CAROLINA CHAPEL HILL (nih funded)
Locations1 site (CHAPEL HILL, UNITED STATES)
Trial IDNIH-10990226 on ClinicalTrials.gov

What this research studies

This research aims to develop a machine learning tool that utilizes visible neural networks to better understand the genetic factors contributing to adult-onset diabetes. By integrating diverse biological data from the Common Fund Data Ecosystem, the project will create a knowledge graph that organizes and connects genetic information with disease outcomes. Patients can benefit from this research as it seeks to translate complex genetic data into actionable health insights, potentially leading to improved treatment strategies for diabetes. The project will also provide a query-able resource for researchers and clinicians to access this integrated data.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with adult-onset diabetes who are interested in understanding the genetic factors influencing their condition.

Not a fit: Patients without a diagnosis of adult-onset diabetes or those not interested in genetic research may not receive benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients with adult-onset diabetes.

How similar studies have performed: Previous research utilizing machine learning and knowledge graphs has shown promise in enhancing our understanding of genetic traits and their implications for health.

Where this research is happening

CHAPEL HILL, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Adult-Onset Diabetes Mellitus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.