Understanding how genes affect brain structure and mental health
Genetic heterogeneity and pleiotropy of neuroimaging and psychiatric phenotypes
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11040317
This study is looking at how our genes and brain structure might be connected to mental health issues, and it’s for anyone interested in understanding more about what influences these conditions and how we might improve treatments.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11040317 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between genetic factors, brain structure, and neuropsychiatric disorders, which are increasingly common. By utilizing advanced techniques like genotyping and magnetic resonance imaging (MRI), the study aims to identify genetic variants that influence brain morphology. It will analyze data from large biobanks to uncover how these genetic factors may contribute to mental health conditions. The findings could provide insights into the biological underpinnings of these disorders and help in developing targeted interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research include adolescents experiencing neuropsychiatric symptoms or those with a family history of such disorders.
Not a fit: Patients with established neuropsychiatric disorders who are not adolescents may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for neuropsychiatric disorders.
How similar studies have performed: Previous research has shown success in identifying genetic factors related to brain structure and neurodevelopment, indicating a promising avenue for this study.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHEN, CHI-HUA — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: CHEN, CHI-HUA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.