Understanding how genes adapt to infections in humans and primates
Genomic signatures of primate-pathogen interactions
This study is looking at how our genes change when we get infections, and it's for anyone interested in understanding how our bodies fight off illnesses, which could lead to better treatments in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-10897760 on NIH RePORTER |
What this research studies
This research investigates the genetic changes that occur in response to infections in both humans and non-human primates. By analyzing large genomic datasets, the team aims to identify specific genetic variations that help organisms survive against pathogens. The study will utilize advanced computational methods to explore how these genetic adaptations have evolved over time, particularly in regions like the Arabian Peninsula. Patients may benefit from insights gained about genetic resilience to infectious diseases, which could inform future treatments and preventive measures.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with a history of infectious diseases or those from diverse genetic backgrounds, particularly from the Arabian Peninsula.
Not a fit: Patients who do not have a genetic predisposition to infectious diseases or those not from the studied geographic regions may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of genetic factors that enhance resistance to infectious diseases, potentially guiding new therapeutic strategies.
How similar studies have performed: Previous research has shown success in understanding genetic adaptations to pathogens, indicating that this approach has the potential for meaningful insights.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Leffler, Ellen — University of Utah
- Study coordinator: Leffler, Ellen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.