Understanding how gait changes can indicate early signs of dementia
Neural mechanisms of gait disturbances as individualized digital biomarker trajectories in preclinical dementia
This study is looking at how changes in walking might be linked to memory problems in people at risk for Alzheimer's and similar conditions, using smart technology to spot these changes early, so you can take part in easy tests from home to help with early detection and support.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10979759 on NIH RePORTER |
What this research studies
This research investigates the relationship between gait disturbances and cognitive decline in individuals at risk for Alzheimer's disease and related dementias. By using advanced AI and computer vision tools, the study aims to identify subtle changes in movement that may signal the onset of dementia before traditional diagnoses are made. Participants may engage in simple physical performance tests that can be monitored at home, making it accessible and convenient. The goal is to develop individualized digital biomarkers that can help in early detection and intervention.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults who are experiencing mild cognitive impairment or have a family history of Alzheimer's disease.
Not a fit: Patients with advanced dementia or those who do not exhibit any cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and more personalized treatment options for patients at risk of dementia.
How similar studies have performed: Previous research has shown promising results in using gait analysis as a potential early indicator of cognitive decline, suggesting that this approach may be effective.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Adeli, Ehsan — Stanford University
- Study coordinator: Adeli, Ehsan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.