Understanding how GABA signaling affects brain development in children with neurodevelopmental disorders
Illuminating GABAergic Signaling in Neurodevelopmental Disorders
This study is looking at how changes in a brain chemical called GABA might affect kids with autism and intellectual disabilities, hoping to find out more about how these changes can lead to challenges in thinking and behavior, which could help improve treatments in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10487398 on NIH RePORTER |
What this research studies
This research investigates the role of GABAergic signaling in neurodevelopmental disorders such as autism and intellectual disabilities. By examining genetic alterations that impact GABA signaling, the study aims to uncover how these changes contribute to cognitive and behavioral issues in children. The research utilizes advanced technologies to analyze the function of specific genes involved in the development of GABAergic neurons, which are crucial for proper brain function. The findings could lead to a better understanding of the underlying mechanisms of these disorders and inform future treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-21 who have been diagnosed with neurodevelopmental disorders such as autism spectrum disorder or intellectual disability.
Not a fit: Patients who do not have neurodevelopmental disorders or are outside the age range of 0-21 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and potential therapies for children with neurodevelopmental disorders.
How similar studies have performed: Previous research has shown promising results in understanding the role of GABA signaling in neurodevelopmental disorders, indicating that this approach has potential for success.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Chao, Hsiao-Tuan — Baylor College of Medicine
- Study coordinator: Chao, Hsiao-Tuan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.