Understanding how GABA-A receptors work in the brain
Structure and Function of GABA-A receptors
This study is looking at how certain brain receptors work and how they respond to different medications, which could help us find better treatments for anxiety and epilepsy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10997244 on NIH RePORTER |
What this research studies
This research investigates the structure and function of GABA-A receptors, which are crucial for regulating brain activity and are involved in conditions like anxiety and epilepsy. The team will use advanced techniques to explore how these receptors interact with various drugs, including those used for anxiety and anesthesia. By examining the receptors in both healthy and diseased brain tissue, the research aims to uncover the mechanisms that control their activity and how they can be targeted for therapeutic purposes. Patients may benefit from insights gained about new treatment options for anxiety disorders and other related conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals suffering from anxiety disorders or epilepsy.
Not a fit: Patients with conditions unrelated to GABA-A receptor function may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for anxiety disorders and epilepsy.
How similar studies have performed: Previous research has shown success in understanding receptor structures and their implications for drug development, making this approach promising.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Hibbs, Ryan E — University of California, San Diego
- Study coordinator: Hibbs, Ryan E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.