Understanding how G protein signaling affects cellular communication in plants
Official title: Phospho- and natural-variant regulation of heterotrimeric G protein signaling
Funded at Pennsylvania State University, the · NIH-11084500 · Data updated 2026-11-12
This study looks at how certain proteins help plants like Arabidopsis thaliana communicate and grow, and by understanding these processes better, we hope to find new ways to improve plant health that could also help people in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project start | May 6, 2024 |
| Project end | February 28, 2029 |
| Funding year | 2025 |
| Award (this year) | $387,544 |
| NIH project number | 5R35GM153492-02 |
| Project ID | NIH-11084500 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals interested in plant biology, agriculture, or those affected by plant-related diseases.
✕Less likely to help
Patients with conditions unrelated to plant biology or agricultural practices may not receive any benefit from this research.
What this research studies
This research investigates the role of heterotrimeric G proteins in cellular signaling pathways, focusing on the model plant Arabidopsis thaliana. By examining how different genetic variants and phosphorylation states of these proteins influence their function, the study aims to uncover the mechanisms behind cellular communication and signaling. The research employs a variety of advanced techniques, including electrophysiology, imaging, and genomic analyses, to explore the effects of G protein signaling on plant health and development. Patients may benefit from insights gained about these fundamental biological processes, which could inform future therapeutic strategies.
Why it matters
Potential benefit: If successful, this research could lead to advancements in understanding cellular signaling that may improve plant health and agricultural practices.
How similar studies have gone: Previous research has shown success in understanding G protein signaling in various biological systems, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Pennsylvania State University, the
University Park, United States Active
Researchers
- Principal investigator: Assmann, Sarah M — Pennsylvania State University, the
- Study coordinator: Assmann, Sarah M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.