NIH-funded research R01 grant

Understanding how fruit flies navigate using sensory information

Official title: CRCNS: Multimodal integration for spatial navigation

Funded at Columbia University Health Sciences · NIH-11162860 · Data updated 2026-11-12

This study looks at how fruit flies use things like light and color to find their way around, helping us understand how their brains create a mental map of their surroundings.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startDecember 5, 2024
Project endNovember 30, 2029
Funding year2025
Award (this year)$405,817
NIH project number1R01NS143142-01
Project IDNIH-11162860 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for benefiting from this research would be individuals interested in cognitive function and navigation, particularly those with conditions affecting spatial awareness.

Less likely to help

Patients with no interest in cognitive function or those not affected by spatial awareness issues may not receive any benefit from this research.

What this research studies

This research investigates how fruit flies use various sensory cues, such as light polarization and color, to determine their direction and navigate their environment. By studying the neural circuits in the fly's brain, particularly in a region known as the central complex, the researchers aim to understand how these circuits integrate different types of information to create a reliable cognitive map. The approach combines experimental techniques with theoretical models to explore the mechanisms behind spatial orientation in these insects.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of cognitive functions related to navigation, which may have implications for developing treatments for cognitive disorders in humans.

How similar studies have gone: Other research has shown success in understanding navigation and cognitive mapping in various species, indicating that this approach is grounded in established scientific principles.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Behnia, Roudabeh — Columbia University Health Sciences
  • Study coordinator: Behnia, Roudabeh

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.