Understanding how fruit flies make decisions based on memory

“CRCNS: Computational principles of memory based decision making in Drosophila”

NIH-funded research Johns Hopkins University · NIH-10653144

This study looks at how fruit flies use their memories to make choices based on different smells, helping us learn more about how decision-making works in all living things, including humans.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10653144 on NIH RePORTER

What this research studies

This research investigates the mechanisms of decision making in fruit flies by examining how they use their memories of past experiences to make choices. The study focuses on the neural connections in the brain of the fruit fly, specifically looking at how certain neurons interact to influence behavior when presented with different odors. By combining experimental techniques with computational modeling, the researchers aim to uncover the underlying principles of memory-based decision making that could have implications for understanding similar processes in humans.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research include individuals with mental health disorders or cognitive impairments related to decision making.

Not a fit: Patients with conditions unrelated to cognitive function or decision-making processes may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of decision-making processes in the brain, potentially leading to new treatments for mental health disorders.

How similar studies have performed: Other research has shown success in using model organisms like fruit flies to understand complex neural processes, indicating that this approach is promising.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental disordersMental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.