Understanding how frog embryos develop at the molecular level
Gene Expression in Amphibian Development
This study looks at how frog embryos grow and develop by exploring how certain genes affect their cells and tissues, which could help scientists understand more about how all vertebrates, including humans, develop.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-11056071 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms behind early vertebrate development using the frog Xenopus. By manipulating embryos through techniques like microinjection and microsurgery, the team studies how specific genes influence cell behavior and tissue movements during critical developmental stages such as gastrulation and neurulation. The research employs advanced imaging techniques and biochemical analyses to uncover the roles of signaling pathways in shaping the embryo. This work aims to provide insights that could benefit the broader scientific community studying vertebrate development.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be scientists and researchers interested in developmental biology and genetics.
Not a fit: Patients with no interest in or relevance to amphibian biology or developmental research may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of developmental biology, potentially leading to advances in regenerative medicine and developmental disorders.
How similar studies have performed: Previous research in developmental biology using similar model organisms has shown promising results, indicating that this approach is well-founded.
Where this research is happening
Berkeley, United States
- University of California Berkeley — Berkeley, United States (Active)
Researchers
- Principal investigator: Harland, Richard M — University of California Berkeley
- Study coordinator: Harland, Richard M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.