Understanding how frailty affects treatment outcomes in older adults
Official title: Mid-Career Mentoring Award For Patient-Oriented Research in Frailty and Health Outcomes
Funded at Hebrew Rehabilitation Center for Aged · NIH-10907455 · Data updated 2026-11-12
This study is looking at how frailty affects the success of medical and surgical treatments for older adults, so we can create better, personalized care plans that help them feel their best.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hebrew Rehabilitation Center for Aged NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $172,477 |
| NIH project number | 5K24AG073527-03 |
| Project ID | NIH-10907455 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults aged 65 and above who may be experiencing frailty.
✕Less likely to help
Patients under the age of 65 or those who do not exhibit signs of frailty may not benefit from this research.
What this research studies
This research investigates the impact of frailty on the effectiveness of medical and surgical treatments in older adults. It aims to personalize treatment plans based on a patient's frailty level, which is crucial for improving health outcomes. The project is led by a geriatrician and epidemiologist who focuses on generating high-quality evidence and training future healthcare professionals in this area. By analyzing Medicare data, the research seeks to identify which patients are most likely to benefit from specific therapies.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for older adults, improving their health outcomes.
How similar studies have gone: Other research has shown promising results in personalizing treatments based on frailty, indicating that this approach has potential for success.
Where this research is happening
-
Hebrew Rehabilitation Center for Aged
Boston, United States Active
Researchers
- Principal investigator: Kim, Dae Hyun — Hebrew Rehabilitation Center for Aged
- Study coordinator: Kim, Dae Hyun
Related research
Other NIH-funded projects on the same topics.
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Investigating frailty and aging in childhood cancer survivors
This study is looking at childhood cancer survivors to see how they might face health challenges similar to older adults as they grow up, and it aims to find ways to help them stay strong and healthy by exploring treatments that could improve their well-being.
-
Exercise-based frailty program for people awaiting lung transplants
A tailored exercise and lifestyle program is being tested to reduce frailty and improve outcomes for people waiting for a lung transplant.
-
AI-enabled bone aging and frailty markers in osteoporosis using advanced imaging
A clinician-scientist is using artificial intelligence with CT scans and epigenetics to better understand early bone aging and osteoporosis in adults.
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Adapting an evidence-based workout program to slow frailty in older women living with HIV
A new program will tailor a proven physical activity plan to help older women with HIV stay stronger, more mobile, and less frail.
-
Time-restricted eating for fatigue and frailty in people with cancer
A 12-week study will test whether eating within a daily 10-hour window helps reduce fatigue and slow frailty in people living with advanced cancer.
-
Functioning, Frailty, and Well-being in aging women
A large NIH grant is funding a study to understand how aging affects physical and mental functioning in women, with the goal of helping maintain independence and quality of life.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.