Understanding how frailty affects osteoporosis and fractures in veterans with rheumatoid arthritis
Quantifying the Impact of Frailty on Osteoporosis and Fractures in Veterans with Rheumatoid Arthritis
['FUNDING_OTHER'] · VA PUGET SOUND HEALTHCARE SYSTEM · NIH-10919768
This study is looking at how rheumatoid arthritis affects veterans by exploring the links between frailty, weak bones, and fractures, with the goal of finding ways to help improve their health and prevent these issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VA PUGET SOUND HEALTHCARE SYSTEM (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-10919768 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between frailty, osteoporosis, and fractures specifically in veterans suffering from rheumatoid arthritis (RA). It aims to understand how chronic inflammation, a hallmark of RA, contributes to both frailty and decreased bone mineral density. By studying inflammatory biomarkers and their impact on these conditions, the research seeks to identify potential interventions that could improve patient outcomes. The study focuses on veterans, who are at a higher risk for these complications, to develop tailored management strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans diagnosed with rheumatoid arthritis, particularly those experiencing frailty or at risk for osteoporosis.
Not a fit: Patients without rheumatoid arthritis or those who are not veterans may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for osteoporosis and fractures in veterans with rheumatoid arthritis.
How similar studies have performed: Previous research has shown associations between inflammatory markers and frailty in the general population, but this specific focus on veterans with RA is relatively novel.
Where this research is happening
SEATTLE, UNITED STATES
- VA PUGET SOUND HEALTHCARE SYSTEM — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WYSHAM, KATHERINE D — VA PUGET SOUND HEALTHCARE SYSTEM
- Study coordinator: WYSHAM, KATHERINE D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.