Understanding how Foxp1 influences the development of retinal cells
Official title: Regulation of Retinal Neurogenesis by Foxp1
Funded at University of Utah · NIH-10991032 · Data updated 2026-11-12
This study is looking at how a gene called Foxp1 helps create important cells in the eye that are needed for good vision, and it hopes to find ways to use this knowledge to help repair damaged retinas and improve treatments for vision loss.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $578,854 |
| NIH project number | 5R01EY035158-02 |
| Project ID | NIH-10991032 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with retinal diseases or injuries that result in the loss of retinal cells.
✕Less likely to help
Patients with retinal conditions that do not involve the loss of early-born retinal cell types may not benefit from this research.
What this research studies
This research investigates the role of the Foxp1 gene in the development of various retinal cell types, which are crucial for normal vision. By using genetic techniques in developing mouse retinas, the researchers aim to understand how Foxp1 regulates the timing and production of these cells from progenitor cells. The study will explore whether manipulating Foxp1 can help regenerate retinal cells that are lost due to disease or injury, potentially leading to new treatments for vision loss. The findings could provide insights into the molecular mechanisms behind retinal cell development and regeneration.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for regenerating retinal cells lost to diseases, improving vision restoration options for patients.
How similar studies have gone: Previous research has shown promising results in understanding retinal cell development, but the specific role of Foxp1 in this context is still being explored, making this a novel investigation.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Vetter, Monica L — University of Utah
- Study coordinator: Vetter, Monica L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.