Understanding how follicle stimulating hormone affects bone and fat in older adults
Elucidating extragonadal functions of follicle stimulating hormone using genetic approaches in mice
This study is looking at how a hormone called follicle stimulating hormone (FSH) affects bone health and metabolism in older adults, with hopes of finding new ways to help prevent osteoporosis and other metabolic issues as we age.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Connecticut Sch of Med/dnt NIH-funded |
| Lab location | 1 site (Farmington, United States) |
| Project ID | NIH-10685473 on NIH RePORTER |
What this research studies
This research investigates the role of follicle stimulating hormone (FSH) in regulating bone density and metabolic function, particularly in older adults. By using genetic approaches in mice, the study aims to uncover how FSH influences tissues beyond the reproductive system, such as bone and adipose (fat) tissue. The findings could lead to new therapeutic strategies to combat osteoporosis and metabolic diseases that are prevalent in the aging population. The research focuses on understanding the physiological mechanisms of FSH to develop effective clinical applications.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those experiencing issues related to bone density and metabolic health.
Not a fit: Patients who are younger and do not have concerns related to bone density or metabolic diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that improve bone health and metabolic function in older adults.
How similar studies have performed: Previous studies have shown promising results regarding the role of FSH in bone and fat regulation, indicating that this research builds on established findings.
Where this research is happening
Farmington, United States
- University of Connecticut Sch of Med/dnt — Farmington, United States (Active)
Researchers
- Principal investigator: Germain-Lee, Emily L — University of Connecticut Sch of Med/dnt
- Study coordinator: Germain-Lee, Emily L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.