Understanding how FMRP affects brain development and function
Administrative Core
This study is looking at how a protein called FMRP affects brain development and function, which could help us find new treatments for fragile X syndrome and improve understanding of the condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10907595 on NIH RePORTER |
What this research studies
This research aims to explore the role of FMRP in regulating human brain development and circuit functions using advanced 2D and 3D model systems, as well as mouse models. By investigating how FMRP influences the translation of specific mRNA targets, the project seeks to identify potential new therapeutic targets for conditions like fragile X syndrome. The collaborative effort involves multiple prestigious institutions, ensuring a comprehensive approach to data collection and analysis. Patients may benefit from insights gained into brain development and potential new treatments.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit include individuals affected by fragile X syndrome or those with related developmental disorders.
Not a fit: Patients with conditions unrelated to fragile X syndrome or those not affected by developmental disorders may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for fragile X syndrome and related conditions.
How similar studies have performed: Previous research has shown promise in understanding the role of FMRP in brain function, indicating that this approach could yield valuable insights.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Jin, Peng — Emory University
- Study coordinator: Jin, Peng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.