Understanding how fluid drainage in the eye affects glaucoma treatments

Dynamic Variable Aqueous Humor Outflow and Glaucoma Therapies in the Human Eye

NIH-funded research University of California, San Diego · NIH-10868428

This study is looking at how fluid drains from the eye to help improve treatments for glaucoma, a condition that can cause vision loss, so that doctors can create personalized therapies that work better for each patient's unique eye needs.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-10868428 on NIH RePORTER

What this research studies

This research investigates the dynamic behavior of aqueous humor outflow in the eye, which is crucial for managing glaucoma, a leading cause of vision loss. By using advanced imaging techniques, the study aims to identify how and why the drainage of eye fluid can vary in different regions, potentially leading to improved treatment strategies. The goal is to develop personalized therapies that target specific areas of the eye where fluid drainage can be enhanced, thereby lowering intraocular pressure more effectively. Patients may benefit from tailored treatments based on their unique eye characteristics.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with glaucoma who are experiencing issues with intraocular pressure management.

Not a fit: Patients with glaucoma who have already undergone irreversible damage to their optic nerve may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatments for glaucoma, potentially preserving vision for many patients.

How similar studies have performed: Previous research has shown promise in understanding fluid dynamics in the eye, suggesting that this approach could lead to significant advancements in glaucoma treatment.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.