Understanding how fibrous tissue interfaces work
Multiscale models of fibrous interface mechanics
['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-11175217
This study is looking into how the connections between different tissues in your body, like tendons and bones, work and why some surgeries don’t heal as well as we hope, with the goal of finding ways to make those repairs stronger and more successful for patients like you.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11175217 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanics of fibrous interfaces in the body, which are crucial for transferring loads between different tissues, such as tendons and bones. It aims to understand why some surgical repairs fail and how the structure of these interfaces can be improved. By developing models and conducting experiments, the research will explore the factors that contribute to the strength and toughness of these interfaces, particularly focusing on the role of disorder in tissue structure. Patients may benefit from insights that could lead to better surgical outcomes and tissue repair techniques.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients undergoing surgeries related to tendon and ligament repairs, particularly those at risk of surgical failure.
Not a fit: Patients with conditions unrelated to fibrous tissue interfaces or those not requiring surgical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved surgical techniques and better recovery outcomes for patients undergoing procedures involving fibrous tissue repairs.
How similar studies have performed: Previous research has shown promise in understanding tissue mechanics, but this specific approach to modeling fibrous interfaces is relatively novel.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GENIN, GUY M — WASHINGTON UNIVERSITY
- Study coordinator: GENIN, GUY M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.