Understanding how fibrin affects health and disease
Official title: MIRA R35: Fibrin(ogen) in regulating health and disease
Funded at Rutgers, the State Univ of N.j. · NIH-11143194 · Data updated 2026-11-12
This study is looking at how a protein in your blood called fibrin helps with healing wounds, fighting cancer, and managing inflammation, and it will also see how different medicines can change how strong or stable this protein is in your body.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers, the State Univ of N.j. NIH-funded |
| Lab location | 1 site (Piscataway, United States) |
| Project start | August 1, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $387,370 |
| NIH project number | 5R35GM155242-02 |
| Project ID | NIH-11143194 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with conditions affecting wound healing, cancer patients, and those experiencing inflammation-related disorders.
✕Less likely to help
Patients with unrelated health issues or those not affected by fibrin-related processes may not benefit from this research.
What this research studies
This research investigates the role of fibrin, a blood plasma protein, in various health conditions such as wound healing, cancer, and inflammation. By applying engineering and biophysical techniques, the study aims to explore how changes in the biochemical environment influence the structure and mechanical properties of fibrin networks. The research will also examine how medications affect the stability and breakdown of these networks, which is crucial for understanding their role in health and disease.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for conditions related to wound healing and cancer.
How similar studies have gone: Previous research has shown promising results in understanding the role of fibrin in health, indicating that this approach has potential for significant advancements.
Where this research is happening
-
Rutgers, the State Univ of N.j.
Piscataway, United States Active
Researchers
- Principal investigator: Tutwiler, Valerie — Rutgers, the State Univ of N.j.
- Study coordinator: Tutwiler, Valerie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.