Understanding how fear and safety memories are processed in the brain

Localizing and modulating competing memories of fear and safety in the human brain

['FUNDING_R01'] · UNIVERSITY OF TEXAS AT AUSTIN · NIH-10991039

This study is looking at how our brains remember feelings of fear and safety, which could help us understand anxiety better and find new ways to help people who struggle with anxiety and stress.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF TEXAS AT AUSTIN (nih funded)
Locations1 site (AUSTIN, UNITED STATES)
Trial IDNIH-10991039 on ClinicalTrials.gov

What this research studies

This research investigates how the human brain encodes, stores, and retrieves memories related to fear and safety. By examining the interactions between these competing memories, the study aims to uncover the underlying mechanisms that contribute to anxiety disorders. The approach involves advanced neuroimaging techniques to identify specific brain regions involved in memory processing. Insights gained from this research could lead to improved therapeutic strategies for individuals suffering from anxiety and stress-related conditions.

Who could benefit from this research

Good fit: Ideal candidates for participation are adults aged 21 and older who experience anxiety or stress-related disorders.

Not a fit: Patients with primary diagnoses unrelated to anxiety or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for anxiety disorders, reducing the likelihood of relapse after therapy.

How similar studies have performed: Previous research in animal models has shown promising results in understanding memory processes, suggesting potential for success in human studies.

Where this research is happening

AUSTIN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.