Understanding how fats are processed and transported in the body
Structure and regulation of lipid metabolism and transport
This study is looking at how certain enzymes that help break down fats work in our bodies, with the goal of finding new ways to treat conditions like obesity, diabetes, and heart disease, so that patients can have better health outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project ID | NIH-11097622 on NIH RePORTER |
What this research studies
This research investigates the molecular and structural mechanisms of lipid-metabolizing enzymes and transport proteins, focusing on their roles in fat storage, insulin sensitivity, and cell behavior. The study specifically examines two key enzymes involved in lipid metabolism: lipin and phospholipase D (PLD). By exploring how these enzymes are activated and regulated, the research aims to uncover insights that could lead to new treatments for conditions like obesity, diabetes, and cardiovascular diseases. Patients may benefit from advancements in therapies targeting these metabolic pathways.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with obesity, diabetes, or cardiovascular diseases.
Not a fit: Patients with unrelated metabolic disorders or those not affected by lipid metabolism issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for obesity, diabetes, and cardiovascular diseases.
How similar studies have performed: Previous research has shown promising results in understanding lipid metabolism, making this approach a continuation of established scientific inquiry.
Where this research is happening
Stony Brook, United States
- State University New York Stony Brook — Stony Brook, United States (Active)
Researchers
- Principal investigator: Airola, Michael Virgil — State University New York Stony Brook
- Study coordinator: Airola, Michael Virgil
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.