Understanding how fat tissue manages iron levels
Adipose Macrophage Iron Handling
This study is looking at how certain immune cells in fat tissue help manage iron levels, which is important for your overall health and can affect conditions like obesity and metabolic disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project ID | NIH-10624942 on NIH RePORTER |
What this research studies
This research investigates the role of macrophages in adipose tissue and how they regulate iron levels necessary for various cellular functions, including the production of red blood cells. By examining the mechanisms through which these immune cells sense and respond to local iron needs, the study aims to uncover how iron management in fat tissue affects overall health. The approach involves analyzing the behavior of macrophages in different environments and their impact on fat tissue dynamics, particularly during changes in body weight. Patients may benefit from insights into how iron regulation can influence conditions related to obesity and metabolic disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with obesity or metabolic disorders who may be affected by iron regulation in adipose tissue.
Not a fit: Patients who do not have issues related to obesity or metabolic disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing obesity-related diseases by targeting iron regulation in fat tissue.
How similar studies have performed: Previous research has shown promising results in understanding the role of macrophages in other tissues, suggesting that this approach could yield valuable insights.
Where this research is happening
Nashville, UNITED STATES
- Vanderbilt University — Nashville, United States (Active)
Researchers
- Principal investigator: Winn, Nathan C — Vanderbilt University
- Study coordinator: Winn, Nathan C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.