Understanding how fat tissue functions in health and disease
Official title: Novel mechanisms regulating adipose tissue function in health and disease
Funded at New York University School of Medicine · NIH-10917236 · Data updated 2026-11-12
This study is looking at how different types of fat cells work in our bodies and how a specific protein called HSF1 might help us find new ways to fight obesity and related health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $452,362 |
| NIH project number | 5R01DK133377-02 |
| Project ID | NIH-10917236 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who are obese or at risk of developing metabolic diseases.
✕Less likely to help
Patients who are not overweight or do not have metabolic disorders may not benefit from this research.
What this research studies
This research investigates the mechanisms that regulate adipose tissue, which is crucial for maintaining energy balance in the body. It focuses on different types of fat cells and aims to understand how they can be manipulated to combat obesity and related metabolic diseases. The study will explore the role of a specific protein, HSF1, in regulating fat cell function and how obesity alters these processes. By analyzing the genetic and epigenetic changes in fat tissue, the research seeks to identify new targets for therapeutic intervention.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for obesity and metabolic diseases by enhancing the function of fat tissue.
How similar studies have gone: Previous research has shown promising results in manipulating fat cell biology to improve metabolic health, indicating that this approach has potential for success.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Mueller, Elisabetta — New York University School of Medicine
- Study coordinator: Mueller, Elisabetta
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.