Understanding how fat tissue around blood vessels affects vascular health
Perivascular Adipose Tissue (PVAT) as a Central Integrator of Vascular Health
This study looks at how a type of fat around blood vessels helps keep your blood pressure in check and your heart healthy, especially when dealing with high-fat diets, and it hopes to find new ways to improve treatments for people with high blood pressure.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan State University NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project ID | NIH-10980455 on NIH RePORTER |
What this research studies
This research investigates the role of perivascular adipose tissue (PVAT) in maintaining vascular health and regulating blood pressure. By examining the interactions between PVAT and blood vessel layers, the study aims to uncover how these tissues work together to influence vascular function. The research will also explore how changes in pressure and stretch affect PVAT's role, particularly in conditions like hypertension induced by high-fat diets. Patients may benefit from insights that could lead to new treatments for blood pressure regulation and cardiovascular health.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who may be experiencing issues related to blood pressure regulation or cardiovascular health.
Not a fit: Patients with no cardiovascular issues or those under 21 years old may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing hypertension and improving cardiovascular health.
How similar studies have performed: Previous research has shown promising results in understanding the role of adipose tissue in vascular health, suggesting that this approach could yield valuable insights.
Where this research is happening
East Lansing, United States
- Michigan State University — East Lansing, United States (Active)
Researchers
- Principal investigator: Watts, Stephanie W — Michigan State University
- Study coordinator: Watts, Stephanie W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.