Understanding how fat tissue affects metabolic health in people with HIV

Assessing the Interrelationship Between Adipose Tissue Thermogenesis and Fibrosis in the Metabolic Health of People Living with HIV

NIH-funded research University of California, San Francisco · NIH-10993034

This study is looking at how fat cells work in people with HIV and how this might affect their risk of diabetes, with the goal of finding ways to help improve their overall health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10993034 on NIH RePORTER

What this research studies

This research investigates the relationship between fat tissue behavior and metabolic health in individuals living with HIV. It focuses on how certain types of fat cells, particularly those that help burn energy, may be suppressed in these individuals, leading to insulin resistance and type 2 diabetes. By examining the role of specific precursor cells that contribute to fat cell development, the study aims to uncover mechanisms that could improve metabolic health in this population. Patients may be involved in assessments that measure fat tissue characteristics and metabolic responses.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who are experiencing metabolic health issues, such as insulin resistance or type 2 diabetes.

Not a fit: Patients who are not living with HIV or those without metabolic health concerns may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for improving metabolic health and reducing diabetes risk in people living with HIV.

How similar studies have performed: Previous research has shown promising results in understanding fat tissue dynamics and metabolic health, suggesting that this approach could yield valuable insights.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.