Understanding how fat tissue affects blood vessel health
Core C (Informatics and Computation Core)
This study is looking at how a type of fat tissue around blood vessels affects heart health, especially when people have conditions like high blood pressure from eating a lot of fatty foods, and it hopes to find helpful information that could improve treatment for patients.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan State University NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project ID | NIH-10980458 on NIH RePORTER |
What this research studies
This research investigates the role of perivascular adipose tissue (PVAT) in maintaining vascular health by analyzing genomic data from both healthy and diseased states. It aims to identify genetic changes that occur when transitioning from health to conditions like hypertension caused by high-fat diets. The project will also develop a predictive computational model to understand how PVAT responds to vascular pressure and its interactions with the nervous system and immune function. Patients may benefit from insights gained about how fat tissue influences blood vessel health and disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to obesity, hypertension, or vascular health issues.
Not a fit: Patients without any vascular health concerns or those not affected by obesity-related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating vascular diseases linked to obesity and hypertension.
How similar studies have performed: Previous research has shown promising results in understanding the role of adipose tissue in vascular health, suggesting that this approach could yield valuable insights.
Where this research is happening
East Lansing, United States
- Michigan State University — East Lansing, United States (Active)
Researchers
- Principal investigator: Bhattacharya, Sudin — Michigan State University
- Study coordinator: Bhattacharya, Sudin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.