Understanding how fat cells use energy
Regulators of adipocyte oxidative metabolism
This study is looking at how fat cells use energy and aims to find new ways to help improve insulin sensitivity and tackle obesity-related issues, which could lead to better treatments for people with metabolic disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10999475 on NIH RePORTER |
What this research studies
This research investigates the mechanisms that regulate how fat cells, or adipocytes, metabolize energy. It focuses on identifying key proteins and genetic factors that influence the oxidative metabolism of these cells, which is crucial for maintaining metabolic health. By exploring the role of a newly identified protein, Mcrip2, and its interaction with other regulatory factors, the study aims to uncover potential therapeutic targets for improving insulin sensitivity and combating obesity-related conditions. Patients may benefit from insights that could lead to new treatments for metabolic disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with metabolic disorders, such as adult-onset diabetes or obesity-related conditions.
Not a fit: Patients who do not have metabolic disorders or related conditions may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving metabolic health and insulin sensitivity in patients.
How similar studies have performed: Previous research has shown success in identifying metabolic regulators, suggesting that this approach may yield valuable insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Kralli, Anastasia — Johns Hopkins University
- Study coordinator: Kralli, Anastasia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.