Understanding how fat cells regulate energy use in the body
Regulation of Mitochondrial Remodeling in Adipose Thermogenesis
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-10889271
This study is looking at a protein called FAM210A in brown fat cells, which help burn energy and keep us warm, to see how it works in cold temperatures, and the results could help find new ways to treat obesity and related health issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-10889271 on ClinicalTrials.gov |
What this research studies
This research investigates the role of a specific protein, FAM210A, in brown fat cells, which are important for burning energy and regulating body temperature. By using advanced imaging techniques and genetically modified mice, the study aims to uncover how FAM210A influences the function of these cells, especially in response to cold temperatures. The findings could lead to new treatments for obesity and related conditions by enhancing our understanding of how fat cells can be manipulated to improve energy expenditure.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or metabolic disorders such as type 2 diabetes.
Not a fit: Patients who are not overweight or do not have metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies for obesity and related metabolic disorders.
How similar studies have performed: Previous research has shown promising results in understanding the role of brown fat in metabolism, suggesting that this approach could yield valuable insights.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YUE, FENG — UNIVERSITY OF FLORIDA
- Study coordinator: YUE, FENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus