Understanding How Fat Cells Burn Energy to Help with Obesity

Regulation of Mitochondrial Remodeling in Adipose Thermogenesis

NIH-funded research University of Florida · NIH-11137719

This work explores how certain fat cells in the body can burn energy to help manage obesity and related conditions like type 2 diabetes.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-11137719 on NIH RePORTER

What this research studies

Obesity is a major health concern linked to conditions like type 2 diabetes, where the body stores too much fat. Our bodies have special brown fat cells that can burn energy and create heat, which could be a way to fight obesity. However, we don't fully understand how these brown fat cells work. This project aims to uncover the hidden molecular controls within these cells to find new ways to help people with obesity.

Who could benefit from this research

Good fit: This foundational research is not directly recruiting patients but aims to benefit individuals living with obesity or type 2 diabetes in the future.

Not a fit: Patients not affected by obesity or type 2 diabetes may not directly benefit from this specific line of research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that help the body burn more calories, potentially aiding in weight management and improving conditions like type 2 diabetes.

How similar studies have performed: This project explores a newly identified protein, FAM210A, in brown fat thermogenesis, representing a novel and largely untested approach in this specific context.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.