Understanding how fat cells affect metabolism and obesity
Lipid metabolism and adipose tissue function
This study is looking at how different types of fat cells in your body affect weight and energy use, especially when it's cold, to help find better ways to treat obesity and related health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10992620 on NIH RePORTER |
What this research studies
This research investigates the roles of different types of fat cells, specifically white and brown adipose tissues, in metabolism and obesity. It focuses on how these cells regulate fat oxidation and energy metabolism, particularly under conditions like cold exposure. By studying a specific protein, ApoL6, which influences fat metabolism, the research aims to uncover mechanisms that could lead to better treatments for obesity and related metabolic disorders. Patients may benefit from insights into how their body processes fat and energy.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults over 21 who are struggling with obesity or related metabolic conditions.
Not a fit: Patients who are under 21 years old or do not have issues related to obesity or metabolic syndrome may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating obesity and metabolic syndrome.
How similar studies have performed: Previous research has shown promising results in understanding fat cell metabolism, making this approach both relevant and potentially impactful.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Liu, Jun — Mayo Clinic Rochester
- Study coordinator: Liu, Jun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.