Understanding how fat cell growth changes with age
Defining the Role of Adipogenesis in Age-Associated Adiposity
This study looks at how getting older can lead to more fat cells, especially around the belly, and how this might cause health problems like insulin resistance and heart issues, with the goal of finding ways to help people age healthier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beckman Research Institute/city of Hope NIH-funded |
| Lab location | 1 site (Duarte, United States) |
| Project ID | NIH-10838463 on NIH RePORTER |
What this research studies
This research investigates how the accumulation of fat cells, particularly in the abdominal area, increases as people age. It aims to understand the process of adipogenesis, which is the formation of new fat cells, and how this process may contribute to health issues like insulin resistance and cardiovascular problems in older adults. By studying the cellular mechanisms involved, the researchers hope to identify when and why these changes occur, which could lead to strategies for preventing excessive fat accumulation and promoting healthier aging.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those over the age of 65, who are experiencing increased abdominal fat accumulation.
Not a fit: Patients who are younger than 65 or those without significant abdominal fat accumulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new interventions that help reduce fat accumulation in older adults, potentially improving their overall health and longevity.
How similar studies have performed: Previous research has shown that understanding cellular processes related to fat accumulation can lead to significant advancements in treating age-related health issues, suggesting that this approach has potential for success.
Where this research is happening
Duarte, United States
- Beckman Research Institute/city of Hope — Duarte, United States (Active)
Researchers
- Principal investigator: Wang, Qiong Annabel — Beckman Research Institute/city of Hope
- Study coordinator: Wang, Qiong Annabel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.