Understanding how fascia affects pain in chronic knee osteoarthritis
Official title: Evaluating the role of fascia structure and innervation in chronic knee OA pain
Funded at University of Florida · NIH-10858190 · Data updated 2026-11-12
This study is looking at how the structure and nerve connections of the fascia around the knee might be linked to the pain and difficulties people with knee osteoarthritis experience, using advanced imaging to help understand these connections better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | September 15, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $510,381 |
| NIH project number | 3UC2AR082196-01S1 |
| Project ID | NIH-10858190 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with chronic knee osteoarthritis who experience significant joint pain and disability.
✕Less likely to help
Patients with acute knee injuries or those without a diagnosis of osteoarthritis may not benefit from this research.
What this research studies
This research investigates the role of fascia structure and its nerve supply in contributing to chronic pain and disability in patients with knee osteoarthritis (OA). By examining changes in the innervation patterns of joint and surrounding tissues, the study aims to uncover how these changes relate to pain symptoms. The research utilizes advanced imaging techniques to assess the physical properties of fascia and its relationship to joint pain. Patients may be involved in both preclinical models and clinical assessments to better understand the underlying mechanisms of their pain.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies for patients suffering from chronic knee osteoarthritis.
How similar studies have gone: Previous research has shown promising results in understanding the role of fascia in musculoskeletal pain, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Allen, Kyle D — University of Florida
- Study coordinator: Allen, Kyle D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.