Understanding how fascia affects pain in chronic knee osteoarthritis

Evaluating the role of fascia structure and innervation in chronic knee OA pain

['FUNDING_OTHER'] · UNIVERSITY OF FLORIDA · NIH-10858190

This study is looking at how the structure and nerve connections of the fascia around the knee might be linked to the pain and difficulties people with knee osteoarthritis experience, using advanced imaging to help understand these connections better.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF FLORIDA (nih funded)
Locations1 site (GAINESVILLE, UNITED STATES)
Trial IDNIH-10858190 on ClinicalTrials.gov

What this research studies

This research investigates the role of fascia structure and its nerve supply in contributing to chronic pain and disability in patients with knee osteoarthritis (OA). By examining changes in the innervation patterns of joint and surrounding tissues, the study aims to uncover how these changes relate to pain symptoms. The research utilizes advanced imaging techniques to assess the physical properties of fascia and its relationship to joint pain. Patients may be involved in both preclinical models and clinical assessments to better understand the underlying mechanisms of their pain.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with chronic knee osteoarthritis who experience significant joint pain and disability.

Not a fit: Patients with acute knee injuries or those without a diagnosis of osteoarthritis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management strategies for patients suffering from chronic knee osteoarthritis.

How similar studies have performed: Previous research has shown promising results in understanding the role of fascia in musculoskeletal pain, suggesting that this approach may yield valuable insights.

Where this research is happening

GAINESVILLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.