Understanding how FAM210A affects heart health
Official title: Deciphering the role of FAM210A in cardiac physiopathology
Funded at University of Rochester · NIH-10895589 · Data updated 2026-11-12
This study is looking at how a gene called FAM210A affects heart health, especially in conditions like heart muscle disease and heart attacks, to help find new ways to treat these issues for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | August 1, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $475,960 |
| NIH project number | 5R01HL169432-02 |
| Project ID | NIH-10895589 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who have been diagnosed with cardiac diseases or conditions related to mitochondrial dysfunction.
✕Less likely to help
Patients with non-cardiac related health issues or those under 21 years old may not receive any benefit from this research.
What this research studies
This research investigates the role of a specific gene, FAM210A, in heart diseases, particularly focusing on how it influences mitochondrial function in heart cells. By using advanced techniques like CRISPR, the study aims to explore the molecular mechanisms that lead to heart conditions such as mitochondrial cardiomyopathy and myocardial infarction. The researchers will analyze how changes in FAM210A expression affect heart cell health and function, which could lead to new therapeutic strategies for heart disease. Patients may benefit from insights gained about the genetic factors contributing to their heart conditions.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for heart diseases by targeting the molecular pathways involved in cardiac dysfunction.
How similar studies have gone: Previous research has shown promising results in understanding mitochondrial dysfunction in heart diseases, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Yao, Peng — University of Rochester
- Study coordinator: Yao, Peng
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.