Understanding how facial motor neuron types develop in health and congenital facial weakness
The Development of Facial Motor Neuron Subtypes in Health and in Congenital Facial Weakness
This study looks at how facial movement nerves develop and how they can be affected in people with congenital facial weakness, hoping to uncover new insights that could lead to better treatments for those experiencing this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11002334 on NIH RePORTER |
What this research studies
This research investigates the development of different types of facial motor neurons and how they are affected in individuals with congenital facial weakness. By examining the underlying biological mechanisms, the study aims to identify how infections and inflammation can alter brain circuitry related to facial movement. Patients may benefit from insights into the causes of their condition and potential new treatment strategies. The research employs advanced techniques to analyze neural connections and their functions in both healthy individuals and those with facial weakness.
Who could benefit from this research
Good fit: Ideal candidates for participation include adults with congenital facial weakness or related neurological conditions.
Not a fit: Patients without facial motor neuron disorders or those who do not have congenital facial weakness may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with facial motor neuron disorders.
How similar studies have performed: Other research has shown promising results in understanding neural circuitry changes due to infections, suggesting potential for success in this area as well.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Carrillo, Gabriela Lizana — Boston Children's Hospital
- Study coordinator: Carrillo, Gabriela Lizana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.