NIH-funded research NIH-funded research

Understanding how exploration develops in adolescents with bulimia nervosa

Official title: Charting the Development of Exploration in Adolescent Bulimia Nervosa: A Neurocomputational Approach

Funded at Virginia Commonwealth University · NIH-11136740 · Data updated 2026-11-12

This study is looking at how teenage girls with bulimia nervosa explore their surroundings and make decisions, by checking out how their brains work compared to girls without the condition, to better understand what might help them during this important time in their development.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVirginia Commonwealth University
NIH-funded
Lab location1 site (Richmond, United States)
Project startMay 1, 2025
Project endApril 30, 2029
Funding year2025
Award (this year)$176,960
NIH project number1K23MH137567-01A1
Project IDNIH-11136740 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescent girls aged 12-20 who are diagnosed with bulimia nervosa.

Less likely to help

Patients who are not adolescents or who do not have a diagnosis of bulimia nervosa may not benefit from this research.

What this research studies

This research investigates the development of exploration strategies in adolescents suffering from bulimia nervosa (BN) by examining the neural circuits involved. It aims to identify how impulsivity and exploration are linked to the onset and maintenance of BN during critical periods of brain development. The study will recruit adolescent girls aged 12-20, comparing those with BN to healthy controls, and will utilize advanced imaging techniques and computational modeling to analyze their behavior and brain activity. Participants will engage in tasks designed to assess their exploration strategies, with follow-ups to track changes over time.

Why it matters

Potential benefit: If successful, this research could lead to more effective, targeted interventions for adolescents with bulimia nervosa.

How similar studies have gone: While there is ongoing research into bulimia nervosa, this specific neurocomputational approach to understanding exploration in adolescents is relatively novel.

Where this research is happening

  • Virginia Commonwealth University
    Richmond, United States
    Active

Researchers

  • Principal investigator: Hagan, Kelsey — Virginia Commonwealth University
  • Study coordinator: Hagan, Kelsey

Related research

Other NIH-funded projects on the same topics.

  • How reward, motivation, and learning drive anorexia and bulimia

    This project looks at how people with anorexia or bulimia experience pleasure, motivation, and learning about food to understand why disordered eating keeps happening.

    NIH research University of California, San Diego · La Jolla, United States · NIH-11251274

  • Brain control during hunger and after eating in bulimia nervosa

    This project looks at whether fasting versus eating changes brain signals that influence self-control in adults with bulimia nervosa.

    NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11243504

  • Understanding how people with anorexia and bulimia process rewards and learn from experiences

    This study is looking at why some people with eating disorders, like anorexia and bulimia, struggle with food even when it hurts them, by exploring how their brains respond to rewards and learn from their experiences, and it invites patients to share their thoughts and feelings about eating.

    NIH research University of California, San Diego · La Jolla, United States · NIH-11046539

  • Understanding brain functions related to cognitive control in bulimia nervosa

    This study is looking at how the brain works when people with bulimia nervosa make decisions about eating, to better understand how their control over food choices changes during eating and fasting, which could lead to new ways to help them.

    NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11010376

  • Understanding how avoidance affects decision-making in anorexia and bulimia

    This study is looking at how the way we learn to avoid bad experiences affects eating disorders like anorexia and bulimia, with the hope of finding better ways to help people who struggle with these issues.

    NIH research University of California, San Diego · La Jolla, United States · NIH-10996019

  • Eating Disorder Dynamic Intervention

    A digital program is tested to help adults with eating disorders by sending real-time, personalized coping tips based on smartphone surveys and sensor data.

    Recruiting Trustees of Dartmouth College · Lebanon, New Hampshire · NCT07600671

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.