NIH-funded research NIH-funded research

Understanding how expectations affect pain and trauma in Veterans

Official title: The role of expectation in the pain-trauma co-morbidity among Veterans

Funded at Veterans Affairs Med Ctr San Francisco · NIH-11071987 · Data updated 2026-11-12

This study is looking at how chronic pain and PTSD are connected in Veterans, and it wants to understand how our thoughts about pain can make things better or worse, so we can find better ways to help those dealing with both issues.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVeterans Affairs Med Ctr San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startApril 1, 2024
Project endMarch 31, 2028
Funding year2025
NIH project number5I01CX000816-06
Project IDNIH-11071987 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are Veterans experiencing both chronic pain and PTSD, particularly those with combat-related trauma.

Less likely to help

Patients who do not have a history of chronic pain or PTSD may not benefit from this research.

What this research studies

This research investigates the complex relationship between chronic pain and Posttraumatic Stress Disorder (PTSD) in Veterans. It aims to uncover the biological mechanisms that link these two conditions, focusing on how expectations about pain can influence their severity. By studying the neural networks involved, the research seeks to identify biological markers that could lead to better prevention and treatment strategies. The ultimate goal is to develop targeted interventions that address both pain and trauma symptoms in a more effective way.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for Veterans suffering from both chronic pain and PTSD.

How similar studies have gone: Previous research has shown promising results in understanding the interplay between pain and trauma, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Veterans Affairs Med Ctr San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Strigo, Irina a — Veterans Affairs Med Ctr San Francisco
  • Study coordinator: Strigo, Irina a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.