Understanding How Exercise Changes Our Bodies
MoTrPAC Genomics, Epigenomics and Transcriptomics Chemical Analysis Site
This project explores the tiny molecular changes that happen in people's bodies when they exercise, helping us understand why physical activity makes us healthier.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11163539 on NIH RePORTER |
What this research studies
We are looking closely at the genetic and cellular changes that occur in people who participate in physical activity programs. Our team will analyze samples from individuals of different ages to see how exercise affects their genes, how genes are turned on or off, and which proteins are being made. This detailed look helps us uncover the hidden ways exercise improves health and could lead to personalized exercise recommendations in the future.
Who could benefit from this research
Good fit: This research involves analyzing samples from people who participate in physical activity interventions, including those aged 0-11 years old and 21+ years old.
Not a fit: Patients who are unable to participate in physical activity or whose conditions are not related to the molecular effects of exercise may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of how exercise benefits health, potentially allowing for more personalized and effective physical activity recommendations for everyone.
How similar studies have performed: While the general benefits of physical activity are well-known, this large-scale consortium aims to comprehensively map the molecular changes, which is a novel and extensive approach.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Sealfon, Stuart C. — Icahn School of Medicine at Mount Sinai
- Study coordinator: Sealfon, Stuart C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.