NIH-funded research R01 grant

Understanding how exercise affects older adults differently

Official title: Multidimensional predictive modeling to understand mechanisms of exercise response heterogeneity in older adults

Funded at Florida Institu /human/machine Cognition · NIH-10980027 · Data updated 2026-11-12

This study is looking at how older adults react to different types of exercise, like running and weightlifting, to find out what makes each person respond differently, so they can create better exercise plans that help everyone stay healthy and feel good as they age.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionFlorida Institu /human/machine Cognition
NIH-funded
Lab location1 site (Pensacola, United States)
Project startSeptember 15, 2024
Project endAugust 31, 2029
Funding year2024
Award (this year)$1,545,208
NIH project number1R01AG089192-01
Project IDNIH-10980027 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults who are interested in improving their physical fitness and overall health.

Less likely to help

Patients who are younger than 21 or those with severe mobility limitations may not benefit from this research.

What this research studies

This research investigates why older adults respond differently to exercise, focusing on both endurance and resistance training. By combining these two types of exercise, the study aims to identify biological factors that influence individual responses to physical activity. The researchers will explore how aging-related changes in the body, such as inflammation and energy production, affect exercise outcomes. This approach could lead to tailored exercise recommendations that enhance health and quality of life for older adults.

Why it matters

Potential benefit: If successful, this research could provide personalized exercise guidelines that improve health outcomes for older adults.

How similar studies have gone: Previous research has shown that tailored exercise programs can significantly improve health outcomes in older adults, suggesting this approach has potential for success.

Where this research is happening

  • Florida Institu /human/machine Cognition
    Pensacola, United States
    Active

Researchers

  • Principal investigator: Bamman, Marcas M — Florida Institu /human/machine Cognition
  • Study coordinator: Bamman, Marcas M

Related research

Other NIH-funded projects on the same topics.

  • Personalized exercise plan to boost health in older adults

    A large study will test how different exercise programs work together to improve health and function in adults aged 21 and up who are aging, focusing on why people respond differently to exercise.

    NIH research Florida Institu /human/machine Cognition · Pensacola, United States · NIH-11389484

  • Adjuvant Nitrite to Enhance Exercise Benefits in Older Adults

    Aging adults who do regular exercise may get more health benefits by taking a nitrate supplement to boost how their bodies respond to exercise.

    NIH research Florida Institu /human/machine Cognition · Pensacola, United States · NIH-11289999

  • Why older adults respond differently to exercise

    This project tests whether combining endurance and strength exercise and measuring body and blood markers can reveal why some older adults improve more than others.

    NIH research Florida Institu /human/machine Cognition · Pensacola, United States · NIH-11189791

  • Improving walking and reducing foot pressure for people with diabetic nerve damage

    This project tries real-time biofeedback to change how adults with diabetic peripheral neuropathy walk so they have lower harmful foot pressure and better walking speed.

    NIH research Florida Institu /human/machine Cognition · Pensacola, United States · NIH-11168786

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.