Understanding how exercise affects older adults differently

Multidimensional predictive modeling to understand mechanisms of exercise response heterogeneity in older adults

['FUNDING_R01'] · FLORIDA INSTITU /HUMAN/MACHINE COGNITION · NIH-10980027

This study is looking at how older adults react to different types of exercise, like running and weightlifting, to find out what makes each person respond differently, so they can create better exercise plans that help everyone stay healthy and feel good as they age.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorFLORIDA INSTITU /HUMAN/MACHINE COGNITION (nih funded)
Locations1 site (PENSACOLA, UNITED STATES)
Trial IDNIH-10980027 on ClinicalTrials.gov

What this research studies

This research investigates why older adults respond differently to exercise, focusing on both endurance and resistance training. By combining these two types of exercise, the study aims to identify biological factors that influence individual responses to physical activity. The researchers will explore how aging-related changes in the body, such as inflammation and energy production, affect exercise outcomes. This approach could lead to tailored exercise recommendations that enhance health and quality of life for older adults.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults who are interested in improving their physical fitness and overall health.

Not a fit: Patients who are younger than 21 or those with severe mobility limitations may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide personalized exercise guidelines that improve health outcomes for older adults.

How similar studies have performed: Previous research has shown that tailored exercise programs can significantly improve health outcomes in older adults, suggesting this approach has potential for success.

Where this research is happening

PENSACOLA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.