Understanding how exercise affects heart and metabolic health
Biochemical profiling to identify cardiometabolic responsiveness to an endurance exercise intervention
['FUNDING_R01'] · BETH ISRAEL DEACONESS MEDICAL CENTER · NIH-11003367
This study is looking at how regular exercise affects heart and metabolic health, and it's for anyone interested in understanding how their body responds to working out, especially with a focus on a special marker that might help predict how well exercise can improve their health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BETH ISRAEL DEACONESS MEDICAL CENTER (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11003367 on ClinicalTrials.gov |
What this research studies
This research investigates how regular exercise influences metabolic and cardiovascular health, focusing on individual differences in response to exercise. By analyzing blood samples, the study aims to identify specific metabolites and proteins that indicate how well a person responds to exercise training. The researchers have previously discovered a potential biomarker, DMGV, which may help predict how effectively individuals can improve their heart and metabolic health through exercise. Participants will contribute to understanding these biochemical pathways and their relation to exercise outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old, particularly those interested in improving their cardiovascular and metabolic health through exercise.
Not a fit: Patients who are not interested in exercise or who have contraindications to physical activity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized exercise recommendations that enhance heart and metabolic health for individuals based on their unique biochemical profiles.
How similar studies have performed: Previous research has shown promise in using metabolic profiling to understand exercise responses, indicating that this approach could yield valuable insights.
Where this research is happening
BOSTON, UNITED STATES
- BETH ISRAEL DEACONESS MEDICAL CENTER — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GERSZTEN, ROBERT E — BETH ISRAEL DEACONESS MEDICAL CENTER
- Study coordinator: GERSZTEN, ROBERT E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.