Understanding how exercise affects fatigue in people with diabetes
Official title: Mechanisms of Fatigability and the Protective Effects of Exercise in People with Diabetes
Funded at Marquette University · NIH-10912519 · Data updated 2026-11-12
This study is looking at why people with pre-diabetes and type 2 diabetes feel more tired when they exercise, focusing on how blood flow and oxygen delivery to their muscles might play a role, and it aims to find ways to help them feel better and perform better during workouts.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Marquette University NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project start | September 15, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $609,795 |
| NIH project number | 5R01AG077688-03 |
| Project ID | NIH-10912519 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are diagnosed with pre-diabetes or type 2 diabetes.
✕Less likely to help
Patients who do not have pre-diabetes or type 2 diabetes may not benefit from this research.
What this research studies
This research investigates the reasons behind increased fatigue during exercise in individuals with pre-diabetes and type 2 diabetes. It focuses on how impaired blood flow and oxygen delivery to muscles may contribute to this fatigue. By examining the vascular responses during exercise, the study aims to identify mechanisms that could help improve exercise performance and overall health in these individuals. Participants may engage in exercise training while their vascular function is monitored.
Why it matters
Potential benefit: If successful, this research could lead to improved exercise strategies that enhance physical performance and health outcomes for individuals with diabetes.
How similar studies have gone: Previous research has shown that exercise can significantly improve health outcomes in individuals with diabetes, suggesting that this approach may yield beneficial results.
Where this research is happening
-
Marquette University
Milwaukee, United States Active
Researchers
- Principal investigator: Sundberg, Christopher — Marquette University
- Study coordinator: Sundberg, Christopher
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.