Understanding how evolution works through genetic mechanisms
Genomic and systemic approaches to evolutionary mechanisms
['FUNDING_OTHER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11011456
This study looks at how genes work together to drive evolution, using simple organisms like yeast and mammals, and aims to uncover helpful information about the genetic factors that can affect diseases and aging, which could benefit patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-11011456 on ClinicalTrials.gov |
What this research studies
This research investigates the fundamental principles of evolution by examining molecular genetic mechanisms and the driving forces behind them. It employs genomic and systemic approaches to assess how individual genes and their interactions contribute to evolutionary processes. By utilizing model systems such as yeast and mammals, the research combines theoretical modeling, computer simulations, and laboratory experiments to explore concepts like epistasis and pleiotropy. Patients may benefit from insights gained about genetic factors influencing diseases and aging.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with genetic disorders or those interested in the genetic basis of aging.
Not a fit: Patients with conditions unrelated to genetic mechanisms or those not affected by aging may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of genetic factors that contribute to diseases and aging, potentially informing new treatment strategies.
How similar studies have performed: Other research has shown success in understanding genetic mechanisms of evolution, making this approach both relevant and promising.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHANG, JIANZHI — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: ZHANG, JIANZHI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.