Understanding how evolution and natural selection shape genetic diversity over time
Population genomic inferences of history and selection across populations and time
This study is looking at how different populations of living things change over time by examining their genes, helping scientists understand how natural selection affects their traits and making tools better for researchers who study these changes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-11019748 on NIH RePORTER |
What this research studies
This research investigates the evolutionary history of populations by analyzing genomic data to understand how natural selection influences genetic variation. The team will develop advanced methods to infer the effects of mutations on fitness across different populations and environments. By applying these methods, they aim to uncover insights into the evolutionary processes that shape life. This research will also enhance existing software tools used in population genomics, making them more effective for researchers in the field.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with genetic disorders or those interested in the genetic basis of diseases within diverse populations.
Not a fit: Patients with conditions unrelated to genetic mutations or those not represented in the studied populations may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a deeper understanding of genetic diseases and inform strategies for their prevention and treatment.
How similar studies have performed: Previous research has shown success in using genomic data to infer evolutionary history, indicating that this approach is both promising and well-established.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Gutenkunst, Ryan — University of Arizona
- Study coordinator: Gutenkunst, Ryan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.